Scientists can peer into cells to get a limited view of their activity using microscopes and other tools. However, cells and ...

RNA sequencing has emerged as a powerful supplement to DNA sequencing for Mendelian disease diagnosis, but clinical translation of diagnostic RNA-seq has not been widely achieved. Researchers at ...

RNA plays critical roles in nearly all biological processes, but current methods for sequencing RNA are significantly limited. This is partially because RNA molecules are chemically modified within ...

Key opportunities lie in next-generation sequencing methods, with hospitals as major end-users and North America as a ...

2026年1月12日，牛津纳米孔技术公司（Oxford Nanopore Technologies）首席执行官Gordon Sanghera在第44届摩根大通医疗健康年会（J.P. Morgan Healthcare Conference, JPM ...

April 14, 2025 – Genome Research (https://genome.org) publishes a second special issue highlighting advances in long-read sequencing applications in biology and medicine. In this second Special Issue, ...

The landscape of next-generation sequencing (NGS) continues to be defined by astonishing technological progress. We continue ...

RNA sequencing (RNA-seq) is a powerful tool in diagnosing Mendelian disorders, but the optimized sequencing depth for this technology has not yet been determined. In a new study published in the ...

细菌与噬菌体之间的军备竞赛已经持续了数十亿年。这场没有硝烟的战争催生了地球上最复杂、最精巧的防御系统。当我们以为自己已经通过Cas9、Cas12a或Cas13窥探到了CRISPR-Cas系统的全貌时，自然界总能以一种令人惊叹的方式提醒我们：我们所知的 ...